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Anti Cancer Drugs
Hycamtin binds to the topoisomerase I-DNA complex and prevents religation of these single strand breaks. This ternary complex interferes with the moving replication fork, which leads to the induction of replication arrest and lethal double-stranded breaks in DNA. The formation of this ternary complex eventually leads to apoptosis (programmed cell death).
Information is up-to-date: 24.01.2017
Detailed description: deeplifecare.com
Hycamtin in a catalog AllBiz