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Bondronat is essentially used for treatment of problems relating to bones. It is used to treat osteoporosis in women post menopause for slowing down the weakening of the bones. It also helps in preventing further damage to bones in patients suffering from breast cancer, in case when the cancer has spread to the bones. It also reduces the probability of hip fractures and other fractures. The Bondronat drug also helps in reducing excess calcium in patients suffering from Hypercalcemia, which is the condition of excess levels of calcium in the blood. It can be taken orally or can be administered as an injection.
Brand Name: Bondronat 6mg,
Content: Ibandronic Acid,
Manufactured By: Roche
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking these tablets it is important that your doctor or pharmacist knows:
When ibandronic acid is given intravenously, it should be diluted and infused over two hours. For hypercalcaemia the dose is determined by the serum calcium, after correction for the albumin concentration. Patients with metastatic breast cancer can be given an intravenous infusion every four weeks or a daily oral dose. Ibandronic acid should not be taken with food as this reduces its bioavailability by 90%. The tablets must be swallowed whole with water and the patient must not lie down for 30 minutes afterwards.
About half of the dose is absorbed by bone. The remainder is excreted unchanged in the urine. No dose adjustment is suggested for hepatic impairment, but the dose should be reduced in patients with severe renal impairment.
Test product, dose and mode of administration or test procedure:
Ibandronic acid, 6mg/6mL vials, IV administration over 15 minutes