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TEMONAT CAPSULE 100 MG MADE BY NATCO PHARMA
WE ARE DEAL ONLY FOR EXPORT ALL OVER THE WORLD
TemoNat(Temozolomide) (tem-oh-ZOHL-oh-mide) belongs to the general group of medicines known as antineoplastics. It is used to treat specific types of cancer of the brain in adults whose tumors have returned and whose tumors have just been diagnosed.
TemoNat(Temozolomide) seems to interfere with the growth of cancer cells, which are then eventually destroyed by the body. Since the growth of normal body cells may also be affected by TemoNat(Temozolomide), other effects will also occur. Some of these may be serious and must be reported to your doctor.
Before you begin treatment with TemoNat(Temozolomide), you and your doctor should talk about the good this medicine will do as well as the risks of using it.
TemoNat(Temozolomide) is to be administered only by or under the immediate supervision of your doctor. It is available in the following dosage form
Before Using This Medicine :
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For TemoNat(Temozolomide), the following should be considered:
Allergies—Tell your doctor if you have ever had any unusual or allergic reaction to dacarbazine or TemoNat(Temozolomide). Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.
Pregnancy—There is a chance that this medicine may cause birth defects if it is taken at the time of conception or if it is taken during pregnancy. You should wait for 6 months after the treatment is finished before becoming pregnant. Studies in rats and rabbits have shown that TemoNat(Temozolomide) causes birth defects in the fetus and other problems (including miscarriages).
Be sure that you have discussed these possible effects with your doctor before taking this medicine. Before taking TemoNat(Temozolomide), make sure your doctor knows if you are pregnant or if you may become pregnant. It is best to use some kind of birth control while you are taking TemoNat(Temozolomide). Tell your doctor right away if you think you have become pregnant while taking TemoNat(Temozolomide).
If you are a man taking TemoNat(Temozolomide) you should be very careful not to father a child up to 6 months after treatment. Use a good form of birth control. Treatment with TemoNat(Temozolomide) may make you sterile. You may want to save and freeze your sperm before you start treatment with TemoNat(Temozolomide) in case this happens.
Breast-feeding—It is not known whether TemoNat(Temozolomide) passes into human breast milk. However, TemoNat(Temozolomide) is not recommended during breast-feeding because it may cause unwanted effects in nursing babies.
Children—Studies on this medicine have been done only in adult patients, and there is no specific information comparing the use of TemoNat(Temozolomide) in children with use in other age groups.
Older adults—Elderly patients may be more sensitive to the effects of TemoNat(Temozolomide). Blood problems such as low platelet (the cell that helps blood to clot) counts and low white blood cell (the cell that helps fight off infections) counts may be especially likely to occur in patients 70 years of age or older.Other medicines—Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking TemoNat(Temozolomide) it is especially important that your health care professional knows if you are taking any of the following:
Acyclovir (e.g., Zovirax) orAnticonvulsants (seizure medicine) orAntidiabetics, oral (diabetes medicine taken by mouth) orAnti-infectives by mouth or by injection (medicine for infection) orAntipsychotics (medicine for mental illness) orCaptopril (e.g., Capoten) orEnalapril (e.g., Vasotec) orFlecainide (e.g., Tambocor) orImipenem orInflammation or pain medicine, except narcotics orLisinopril (e.g., Prinivil, Zestril) orMaprotiline (e.g., Ludiomil) orPenicillamine (e.g., Cuprimine) orPimozide (e.g., Orap) orProcainamide (e.g., Pronestyl) orPromethazine (e.g., Phenergan) orRamipril (e.g., Altace) orSulfasalazine (e.g., Azulfidine) orTiopronin (e.g., Thiola) orTocainide (e.g., Tonocard) orTricyclic antidepressants (medicine for depression) orTrimeprazine (e.g., Temaril)—Concurrent use of these agents with TemoNat(Temozolomide) may cause blood disordersAlpha Interferons (e.g., Intron A, Roferon-A) orAmphotericin B by injection (e.g., Fungizone) orAntineoplastics, other (cancer medicine) orAntithyroid agents (medicine for overactive thyroid) orAzathioprine (e.g., Imuran) orChloramphenicol (e.g., Chloromycetin) orColchicine orFlucytosine (e.g., Ancoban) orGanciclovir (e.g., Cytovene) orZidovudine (e.g., AZT, Retrovir)—Concurrent use of these agents with TemoNat(Temozolomide) increases the risk of infection
If you have ever been treated with radiation or cancer medicines—TemoNat(Temozolomide) may increase the effects that these medicines or radiation therapy may have on the bloodOther medical problems—The presence of other medical problems may affect the use of TemoNat(Temozolomide). Make sure you tell your doctor if you have any other medical problems, especially:
Bone marrow depression, existing orInfection—There may be an increased risk of infections or worsening infections because of the body's reduced ability to fight themChickenpox (including recent exposure) orHerpes zoster (shingles)—Risk of severe disease affecting other parts of the bodyKidney disease orLiver disease— TemoNat(Temozolomide) should be used with caution Proper Use of This Medicine
Take this medicine only as directed . Do not take more or less of it and do not take it for a longer time than directed. To do so may increase the chance of unwanted side effects. This is especially important for elderly patients, who may be more sensitive to the effects of this medicine.
TemoNat(Temozolomide) often causes nausea and vomiting. However, it is very important that you continue to take the medicine, even if you begin to feel ill . Taking the medicine on an empty stomach or at bedtime may help to lessen the nausea. Ask your health care professional for other ways to help lessen these effects.
TemoNat(Temozolomide) should be taken at the same time each day in relation to meals.
TemoNat(Temozolomide) capsules should be swallowed whole with a full glass of water. The capsules should not be chewed, crushed or broken open . If the capsules are opened accidentally, do not allow the powder to come into contact with your skin or into your mouth or nose. Be careful not to inhale the contents of the capsule.
Dosing—The dose of TemoNat(Temozolomide) will be different for different patients. The dose that is used will depend on a number of things, including the patient's body size and various laboratory test results. If you are taking TemoNat(Temozolomide) at home, follow your doctor's orders or the directions on the label . If you have any questions about the proper dose of TemoNat(Temozolomide), ask your doctor.
Missed dose—If you miss a dose of this medicine, do not double the next one. Check with your doctor for further instructions.
Storage—To store this medicine:
Keep out of the reach of children.
Store away from heat and direct light.
Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down.
Do not keep outdated medicine or medicine no longer needed. Ask your health care professional how you should dispose of any medicine you do not use. Be sure that any discarded medicine is out of the reach of children